Dulcolax - purgative. Causes irritation of the receptor of bowels, exerts direct impact at mucous membrane of intestines, strengthening its peristaltics and increasing secretion of slime in a large intestine. It is effective at hypotonic and colonic inertia for regulation of fecal matter. Sometimes it is taken at preparation for surgeries, instrumental examinationand and radiological researches.
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Dulcolax (bisacodil) is a prodrug. When ingested in an alkaline environment, hydrolysis takes place forming a substance that exerts an irritant effect on the gastrointestinal mucosa (the secretion of mucus in the large intestine increases, its peristalsis accelerates and intensifies). When ingested, it starts acting in 6-10 hours, being taken before the bedtime the drug starts acting in 8-12 hours.
- acute constipation;
- atony of the intestine after prolonged bed rest, changes in diet or the environment;
- hypotension and flaccid peristalsis of the colon (for example, in elderly patients);
- evacuation of the intestine before the examinations (X-ray, endoscopic), before and after operations, with severe cardiovascular diseases, during childbirth;
Mode of application
The drug may be indicated per os (through the mouth) and per rectum (in the rectum). Adults - 1-3 dragees per night or 1-2 suppositories (suppositories) rectally (in the rectum). If necessary, take an additional 1-3 tablets in the morning 30 minutes before taking breakfast. Usual single dose for adults is 5-10 mg (1 - 2 tablets). Doses for children are set according to their exact age.
acute inflammatory diseases of the abdominal cavity (appendicitis, diverticulitis),
lack of potassium,
bleeding from the gastrointestinal tract,
hypersensitivity to bisacodil.
The most commonly reported adverse reactions during the use of the drug are spastic abdominal pain and diarrhea.
On the part of the digestive system: spasmodic pains or discomfort in the abdomen, diarrhea (dehydration, muscle weakness, convulsions, lowering blood pressure), nausea, vomiting, minor amounts of blood in the stool, anorectal discomfort, colitis.
On the part of the nervous system: dizziness, fainting.
These side effects arising from the usage of the drug are associated with vasovagal reaction (i.e., due to intestinal spasm, straining during defecation).
On the part of the immune system: hypersensitivity, angio-edema, anaphylactic reactions.